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Motoric Cognitive Risk Syndrome: Prevalence and Cognitive Performance

29 Pages Posted: 26 Jul 2021

See all articles by Isabel Márquez-Lugo

Isabel Márquez-Lugo

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento

Elkin Garcia-Cifuentes

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento

Angela Iragorri

Hospital Universitario San Ignacio - Unidad de Neurologia

Felipe Ramirez Velandia

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento

Ana María Saavedra

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento

Miguel German Borda

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento

Margarita Osuna

University of Southern California - Leonard Davis School of Gerontology

Jennifer A. Ailshire

University of Southern California - Leonard Davis School of Gerontology

Carlos Cano-Gutierrez

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento

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Abstract

Introduction: Cognitive decline and dementia have a significant impact in older adults.  Motoric Cognitive Risk Syndrome (MCRS) is a pre-dementia stage where slow gait speed and subjective memory complaints are present, MCRS increase the risk of outcomes such as frailty, dementia, disability, falls and overall mortality.  

Methods: Data from the SABE Colombia study (Health, Well-Being, and Aging) conducted in 2015 in community-dwelling adults aged 60 years and older. A sub-sample of 19,004 participants was obtained.

Results: A prevalence of 5,45% of MCRS. After adjusting for confounding variables MCRS was associated with MMSE (OR 0·90, CI 0·82-0·99; p 0·028) and frailty (OR 9·1, CI 3·26-25·47, p 0·000; OR 21·38, CI 6·30-72·57, p 0·000).

Conclusion: This study found a prevalence of 5·45% of MCRS in Colombian older adults. We found an association between cognitive performance (MMSE) and frailty with MCRS. Our results increase the awareness of a pre-dementia stages different to Mild Cognitive Impairment (MCI), as these individuals are at greater risk than those with MCI to develop dementia.

Funding: The database used of this study is part of a larger project funded by the Administrative Department of Science, Technology and Innovation (Colciencias) and the Ministry of Health and Social Protection of Colombia (SABE Study 2015, ID No. 764).

Declaration of Interest: None to declare.

Suggested Citation

Márquez-Lugo, Isabel and Garcia-Cifuentes, Elkin and Iragorri, Angela and Ramirez Velandia, Felipe and Saavedra, Ana María and Borda, Miguel German and Osuna, Margarita and Ailshire, Jennifer A. and Cano-Gutierrez, Carlos, Motoric Cognitive Risk Syndrome: Prevalence and Cognitive Performance. Available at SSRN: https://ssrn.com/abstract=3893561 or http://dx.doi.org/10.2139/ssrn.3893561

Isabel Márquez-Lugo (Contact Author)

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento ( email )

Bogotá
Colombia

Elkin Garcia-Cifuentes

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento ( email )

Bogotá
Colombia

Angela Iragorri

Hospital Universitario San Ignacio - Unidad de Neurologia ( email )

Bogotá
Colombia

Felipe Ramirez Velandia

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento ( email )

Bogotá
Colombia

Ana María Saavedra

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento ( email )

Bogotá
Colombia

Miguel German Borda

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento ( email )

Bogotá
Colombia

Margarita Osuna

University of Southern California - Leonard Davis School of Gerontology ( email )

Los Angeles, CA
United States

Jennifer A. Ailshire

University of Southern California - Leonard Davis School of Gerontology ( email )

Los Angeles, CA
United States

Carlos Cano-Gutierrez

Pontifical University Javeriana Cali - Semillero de Neurociencias y Envejecimiento ( email )

Bogotá
Colombia

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